While I fully realize that CW focuses on the style of Eighties horror movies, rather than traditional Gothic, or metaphysical Cthulhu, Kult, etc, I can't help but wonder how to model the latter under CW.
With the games we presently have in the Pacesetter line most of the elements seem to be available. The biggest puzzle is perhaps how to model the Cosmic level Things Man Was Not Meant To Know. Cultists and lesser creatures are easy and covered between PTs, magic from Majus, and CW creatures.
The plots and schemes of inhuman agencies need not be fundamentally different in game mechanics to those of human agencies, they are mostly CM driven story elements in any case.
What I am wondering is how to handle the rare but climactic encounters with things like the Hunting horrors of Nyarlathotep or the Children of Yog-Sothoth such as appeared at the end of Dunwhich Horror. Or even Cthulhu himself. Azathoth and Nyarlathotep as well as Yog Sothoth seem to me to be beyond game mechanics. I would treat them the way Mouse Guard treated a snapping turtle in one scenario. This is a Godzilla scale monster, nothing the PCs can do will be able to harm it. In other words find a way of dealing with it other than direct combat.
How would you model Clive Barker, HP Lovecraft, and others who play with the idea that reality is not "real" at least not in the way we think it is?