The standard MF setup is that whatever form the apocalypse took, it happened long ago and technology is pretty much medieval, with only scavenged technology that you have a chance of understanding.
What about using MF to model a setting where the apocalypse is still a relatively recent memory and technology hasn't gone down the tube. People can still use computers, repair engines, and refurbish (and occasionally produce) simple firearms, etc. Occasional holdouts of high tech understanding occur. Something like Fallout or, what's this other game I'm thinking about... Holes? Tears? Punctures? It'll come to me...
In a similar vein, how about using a sort of Mutants and Mazes variant that supports modern-type characters trying to survive as the apocalypse rages around them? Similar to another game, Nutty Earth? Crazy Earth? Chaos World?
Looking at the Action Resolution table, that seems to be a good first step, but is there any other guidelines for increasing the level of technical knowledge?